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Spatially informed cell-type deconvolution for spatial transcriptomics

Spatially informed cell-type deconvolution for spatial transcriptomics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9464662

Spatially informed cell-type deconvolution for spatial transcriptomics

About this item

Full title

Spatially informed cell-type deconvolution for spatial transcriptomics

Author / Creator

Publisher

New York: Nature Publishing Group US

Journal title

Nature biotechnology, 2022-09, Vol.40 (9), p.1349-1359

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Many spatially resolved transcriptomic technologies do not have single-cell resolution but measure the average gene expression for each spot from a mixture of cells of potentially heterogeneous cell types. Here, we introduce a deconvolution method, conditional autoregressive-based deconvolution (CARD), that combines cell-type-specific expression in...

Alternative Titles

Full title

Spatially informed cell-type deconvolution for spatial transcriptomics

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9464662

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9464662

Other Identifiers

ISSN

1087-0156,1546-1696

E-ISSN

1546-1696

DOI

10.1038/s41587-022-01273-7

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