Antibody stabilization for thermally accelerated deep immunostaining
Antibody stabilization for thermally accelerated deep immunostaining
About this item
Full title
Author / Creator
Lai, Hei Ming , Tang, Yumi , Lau, Zachary Y. H. , Campbell, Robert A. A. , Yau, Juno C. N. , Chan, Caleb C. Y. , Chan, Danny C. W. , Wong, Tin Yan , Wong, Harriet K. T. , Yan, Leo Y. C. , Wu, William K. K. , Wong, Sunny H. , Kwok, Ka-Wai , Wing, Yun-Kwok , Lam, Henry H. N. , Ng, Ho-Keung , Mrsic-Flogel, Thomas D. , Mok, Vincent C. T. , Chan, Jason Y. K. and Ko, Ho
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Antibodies have diverse applications due to their high reaction specificities but are sensitive to denaturation when a higher working temperature is required. We have developed a simple, highly scalable and generalizable chemical approach for stabilizing off-the-shelf antibodies against thermal and chemical denaturation. We demonstrate that the sta...
Alternative Titles
Full title
Antibody stabilization for thermally accelerated deep immunostaining
Authors, Artists and Contributors
Author / Creator
Tang, Yumi
Lau, Zachary Y. H.
Campbell, Robert A. A.
Yau, Juno C. N.
Chan, Caleb C. Y.
Chan, Danny C. W.
Wong, Tin Yan
Wong, Harriet K. T.
Yan, Leo Y. C.
Wu, William K. K.
Wong, Sunny H.
Kwok, Ka-Wai
Wing, Yun-Kwok
Lam, Henry H. N.
Ng, Ho-Keung
Mrsic-Flogel, Thomas D.
Mok, Vincent C. T.
Chan, Jason Y. K.
Ko, Ho
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9467915
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9467915
Other Identifiers
ISSN
1548-7091,1548-7105
E-ISSN
1548-7105
DOI
10.1038/s41592-022-01569-1
