Self-supervised contrastive learning for integrative single cell RNA-seq data analysis
Self-supervised contrastive learning for integrative single cell RNA-seq data analysis
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Author / Creator
Han, Wenkai , Cheng, Yuqi , Chen, Jiayang , Zhong, Huawen , Hu, Zhihang , Chen, Siyuan , Zong, Licheng , Hong, Liang , Chan, Ting-Fung , King, Irwin , Gao, Xin and Li, Yu
Publisher
England: Oxford University Press
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Language
English
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Publisher
England: Oxford University Press
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Abstract
We present a novel self-supervised Contrastive LEArning framework for single-cell ribonucleic acid (RNA)-sequencing (CLEAR) data representation and the downstream analysis. Compared with current methods, CLEAR overcomes the heterogeneity of the experimental data with a specifically designed representation learning task and thus can hand...
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Full title
Self-supervised contrastive learning for integrative single cell RNA-seq data analysis
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9487595
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9487595
Other Identifiers
ISSN
1467-5463,1477-4054
E-ISSN
1477-4054
DOI
10.1093/bib/bbac377