Experimental method for haplotype phasing across the entire length of chromosome 21 in trisomy 21 ce...
Experimental method for haplotype phasing across the entire length of chromosome 21 in trisomy 21 cells using a chromosome elimination technique
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England: Nature Publishing Group
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English
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England: Nature Publishing Group
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Modern sequencing technologies produce a single consensus sequence without distinguishing between homologous chromosomes. Haplotype phasing solves this limitation by identifying alleles on the maternal and paternal chromosomes. This information is critical for understanding gene expression models in genetic disease research. Furthermore, the haplot...
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Experimental method for haplotype phasing across the entire length of chromosome 21 in trisomy 21 cells using a chromosome elimination technique
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9510051
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9510051
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ISSN
1434-5161
E-ISSN
1435-232X
DOI
10.1038/s10038-022-01049-6
