PFKFB3 works on the FAK-STAT3-SOX2 axis to regulate the stemness in MPM
PFKFB3 works on the FAK-STAT3-SOX2 axis to regulate the stemness in MPM
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Background
Malignant pleural mesothelioma (MPM) is an aggressive neoplasm and often acquires chemoresistance by increasing stemness in tumour tissue, thereby generating cancer stem cells (CSCs). CSCs escape treatment by deploying metabolic pathways to trigger dormancy or proliferation, also gaining the ability to exit and re-enter the cell cycle...
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Full title
PFKFB3 works on the FAK-STAT3-SOX2 axis to regulate the stemness in MPM
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9519537
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9519537
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ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/s41416-022-01867-7
