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Ubiquitin-binding domain in ABIN1 is critical for regulating cell death and inflammation during deve...

Ubiquitin-binding domain in ABIN1 is critical for regulating cell death and inflammation during deve...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9525631

Ubiquitin-binding domain in ABIN1 is critical for regulating cell death and inflammation during development

About this item

Full title

Ubiquitin-binding domain in ABIN1 is critical for regulating cell death and inflammation during development

Publisher

London: Nature Publishing Group UK

Journal title

Cell death and differentiation, 2022-10, Vol.29 (10), p.2034-2045

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

ABIN1 is a polyubiquitin-binding protein known to regulate NF-κB activation and cell death signaling. Mutations in
Abin1
can cause severe immune diseases in human, such as psoriasis, systemic lupus erythematosus, and systemic sclerosis. Here, we generated mice that disrupted the ubiquitin-binding domain of ABIN1 (
Abin1
UBD/UBD
) die...

Alternative Titles

Full title

Ubiquitin-binding domain in ABIN1 is critical for regulating cell death and inflammation during development

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9525631

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9525631

Other Identifiers

ISSN

1350-9047

E-ISSN

1476-5403

DOI

10.1038/s41418-022-00994-1

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