Progranulin regulates the development and function of NKT2 cells through EZH2 and PLZF
Progranulin regulates the development and function of NKT2 cells through EZH2 and PLZF
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Author / Creator
Du, Zuochen , Huang, Lu , Dai, Xin , Yang, Di , Niu, Linlin , Miller, Heather , Ruan, Changshun , Li, Han , Hu, Leling , Zhou, Lijia , Jian, Ding , Sun, Jian , Shi, Xiaoqi , Huang, Pei , Chen, Yan , Zhao, Xiaodong and Liu, Chaohong
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
T helper 2 (Th2) cytokine production by invariant natural killer T (iNKT) cells is involved in the development of asthma, but the regulation of Th2 cytokines in iNKT cells remains unknown. Although it is known that progranulin (PGRN) induces the production of Th2 cytokines in iNKT cells in vivo, the underlying mechanism is not clear. This study aim...
Alternative Titles
Full title
Progranulin regulates the development and function of NKT2 cells through EZH2 and PLZF
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9525702
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9525702
Other Identifiers
ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/s41418-022-00973-6
