PolyGA targets the ER stress-adaptive response by impairing GRP75 function at the MAM in C9ORF72-ALS...
PolyGA targets the ER stress-adaptive response by impairing GRP75 function at the MAM in C9ORF72-ALS/FTD
About this item
Full title
Author / Creator
Pilotto, Federica , Schmitz, Alexander , Maharjan, Niran , Diab, Rim , Odriozola, Adolfo , Tripathi, Priyanka , Yamoah, Alfred , Scheidegger, Olivier , Oestmann, Angelina , Dennys, Cassandra N. , Sinha Ray, Shrestha , Rodrigo, Rochelle , Kolb, Stephen , Aronica, Eleonora , Di Santo, Stefano , Widmer, Hans Rudolf , Charlet-Berguerand, Nicolas , Selvaraj, Bhuvaneish T , Chandran, Siddharthan , Meyer, Kathrin , Zuber, Benoît , Goswami, Anand , Weis, Joachim and Saxena, Smita
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
ER stress signaling is linked to the pathophysiological and clinical disease manifestations in amyotrophic lateral sclerosis (ALS). Here, we have investigated ER stress-induced adaptive mechanisms in
C9ORF72
-ALS/FTD, focusing on uncovering early endogenous neuroprotective mechanisms and the crosstalk between pathological and adaptive respons...
Alternative Titles
Full title
PolyGA targets the ER stress-adaptive response by impairing GRP75 function at the MAM in C9ORF72-ALS/FTD
Authors, Artists and Contributors
Author / Creator
Schmitz, Alexander
Maharjan, Niran
Diab, Rim
Odriozola, Adolfo
Tripathi, Priyanka
Yamoah, Alfred
Scheidegger, Olivier
Oestmann, Angelina
Dennys, Cassandra N.
Sinha Ray, Shrestha
Rodrigo, Rochelle
Kolb, Stephen
Aronica, Eleonora
Di Santo, Stefano
Widmer, Hans Rudolf
Charlet-Berguerand, Nicolas
Selvaraj, Bhuvaneish T
Chandran, Siddharthan
Meyer, Kathrin
Zuber, Benoît
Goswami, Anand
Weis, Joachim
Saxena, Smita
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9547809
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9547809
Other Identifiers
ISSN
0001-6322
E-ISSN
1432-0533
DOI
10.1007/s00401-022-02494-5