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Anabolic actions of parathyroid hormone in a hypophosphatasia mouse model

Anabolic actions of parathyroid hormone in a hypophosphatasia mouse model

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9568459

Anabolic actions of parathyroid hormone in a hypophosphatasia mouse model

About this item

Full title

Anabolic actions of parathyroid hormone in a hypophosphatasia mouse model

Publisher

London: Springer London

Journal title

Osteoporosis international, 2022-11, Vol.33 (11), p.2423-2433

Language

English

Formats

Publication information

Publisher

London: Springer London

More information

Scope and Contents

Contents

Summary
Hypophosphatasia, the rare heritable disorder caused by TNAP enzyme mutations, presents wide-ranging severity of bone hypomineralization and skeletal abnormalities. Intermittent PTH (1-34) increased long bone volume in
Alpl
-/-
mice but did not alter the skull phenotype. PTH may have therapeutic value for adults with TNAP defici...

Alternative Titles

Full title

Anabolic actions of parathyroid hormone in a hypophosphatasia mouse model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9568459

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9568459

Other Identifiers

ISSN

0937-941X

E-ISSN

1433-2965

DOI

10.1007/s00198-022-06496-7

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