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Behavioral and neurochemical interactions of the tricyclic antidepressant drug desipramine with L-DO...

Behavioral and neurochemical interactions of the tricyclic antidepressant drug desipramine with L-DO...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9584871

Behavioral and neurochemical interactions of the tricyclic antidepressant drug desipramine with L-DOPA in 6-OHDA-lesioned rats. Implications for motor and psychiatric functions in Parkinson’s disease

About this item

Full title

Behavioral and neurochemical interactions of the tricyclic antidepressant drug desipramine with L-DOPA in 6-OHDA-lesioned rats. Implications for motor and psychiatric functions in Parkinson’s disease

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Psychopharmacology, 2022-11, Vol.239 (11), p.3633-3656

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Rationale
The pharmacological effects of antidepressants in modulating noradrenergic transmission as compared to serotonergic transmission in a rat model of Parkinson’s disease under chronic L-DOPA therapy are insufficiently explored.
Objectives
The aim of the present study was to investigate the effect of the tricyclic antidepressant desi...

Alternative Titles

Full title

Behavioral and neurochemical interactions of the tricyclic antidepressant drug desipramine with L-DOPA in 6-OHDA-lesioned rats. Implications for motor and psychiatric functions in Parkinson’s disease

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9584871

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9584871

Other Identifiers

ISSN

0033-3158,1432-2072

E-ISSN

1432-2072

DOI

10.1007/s00213-022-06238-x

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