Modulation of DNA Methylation/Demethylation Reactions Induced by Nutraceuticals and Pollutants of Ex...
Modulation of DNA Methylation/Demethylation Reactions Induced by Nutraceuticals and Pollutants of Exposome Can Promote a C > T Mutation in the Breast Cancer Predisposing Gene PALB2
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Background: Deregulation of DNA methylation/demethylation reactions may be the source of C > T mutation via active deamination of 5-methylcytosine to thymine. Exposome, that is to say, the totality of exposures to which an individual is subjected during their life, can deregulate these reactions. Thus, one may wonder whether the exposome can induce...
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Modulation of DNA Methylation/Demethylation Reactions Induced by Nutraceuticals and Pollutants of Exposome Can Promote a C > T Mutation in the Breast Cancer Predisposing Gene PALB2
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9590087
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9590087
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ISSN
2075-4655
E-ISSN
2075-4655
DOI
10.3390/epigenomes6040032
