Integrated host-microbe plasma metagenomics for sepsis diagnosis in a prospective cohort of critical...
Integrated host-microbe plasma metagenomics for sepsis diagnosis in a prospective cohort of critically ill adults
About this item
Full title
Author / Creator
Kalantar, Katrina L. , Neyton, Lucile , Abdelghany, Mazin , Mick, Eran , Jauregui, Alejandra , Caldera, Saharai , Serpa, Paula Hayakawa , Ghale, Rajani , Albright, Jack , Sarma, Aartik , Tsitsiklis, Alexandra , Leligdowicz, Aleksandra , Christenson, Stephanie A. , Liu, Kathleen , Kangelaris, Kirsten N. , Hendrickson, Carolyn , Sinha, Pratik , Gomez, Antonio , Neff, Norma , Pisco, Angela , Doernberg, Sarah B. , Derisi, Joseph L. , Matthay, Michael A. , Calfee, Carolyn S. and Langelier, Charles R.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
We carried out integrated host and pathogen metagenomic RNA and DNA next generation sequencing (mNGS) of whole blood (
n
= 221) and plasma (
n
= 138) from critically ill patients following hospital admission. We assigned patients into sepsis groups on the basis of clinical and microbiological criteria. From whole-blood gene expression...
Alternative Titles
Full title
Integrated host-microbe plasma metagenomics for sepsis diagnosis in a prospective cohort of critically ill adults
Authors, Artists and Contributors
Author / Creator
Neyton, Lucile
Abdelghany, Mazin
Mick, Eran
Jauregui, Alejandra
Caldera, Saharai
Serpa, Paula Hayakawa
Ghale, Rajani
Albright, Jack
Sarma, Aartik
Tsitsiklis, Alexandra
Leligdowicz, Aleksandra
Christenson, Stephanie A.
Liu, Kathleen
Kangelaris, Kirsten N.
Hendrickson, Carolyn
Sinha, Pratik
Gomez, Antonio
Neff, Norma
Pisco, Angela
Doernberg, Sarah B.
Derisi, Joseph L.
Matthay, Michael A.
Calfee, Carolyn S.
Langelier, Charles R.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9613463
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9613463
Other Identifiers
ISSN
2058-5276
E-ISSN
2058-5276
DOI
10.1038/s41564-022-01237-2