Tau antibody 77G7 targeting microtubule binding domain suppresses proteopathic tau to seed tau aggre...
Tau antibody 77G7 targeting microtubule binding domain suppresses proteopathic tau to seed tau aggregation
About this item
Full title
Author / Creator
Li, Longfei , Miao, Jin , Chu, Dandan , Jin, Nana , Tung, Yunn Chyn , Dai, Chun‐Ling , Hu, Wen , Gong, Cheng‐Xin , Iqbal, Khalid and Liu, Fei
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
England: John Wiley & Sons, Inc
Subjects
More information
Scope and Contents
Contents
Introduction
Neurofibrillary tangle (NFT) of hyperphosphorylated tau is a hallmark of Alzheimer's disease (AD) and related tauopathies. Tau lesion starts in the trans‐entorhinal cortex, from where it spreads to limbic regions, followed by neocortical areas. The regional distribution of NFTs associates with the progression of AD. Accumulating evi...
Alternative Titles
Full title
Tau antibody 77G7 targeting microtubule binding domain suppresses proteopathic tau to seed tau aggregation
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9627375
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9627375
Other Identifiers
ISSN
1755-5930
E-ISSN
1755-5949
DOI
10.1111/cns.13970
