Epigenome-wide analysis of T-cell large granular lymphocytic leukemia identifies BCL11B as a potenti...
Epigenome-wide analysis of T-cell large granular lymphocytic leukemia identifies BCL11B as a potential biomarker
About this item
Full title
Author / Creator
Johansson, Patricia , Laguna, Teresa , Ossowski, Julio , Pancaldi, Vera , Brauser, Martina , Dührsen, Ulrich , Keuneke, Lara , Queiros, Ana , Richter, Julia , Martín-Subero, José I. , Siebert, Reiner , Schlegelberger, Brigitte , Küppers, Ralf , Dürig, Jan , Murga Penas, Eva M. , Carillo-de Santa Pau, Enrique and Bergmann, Anke K.
Publisher
Germany: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Germany: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
The molecular pathogenesis of T-cell large granular lymphocytic leukemia (T-LGLL), a mature T-cell leukemia arising commonly from T-cell receptor αβ-positive CD8
memory cytotoxic T cells, is only partly understood. The role of deregulated methylation in T-LGLL is not well known. We analyzed the epigenetic profile of T-LGLL cells of 11 patients c...
Alternative Titles
Full title
Epigenome-wide analysis of T-cell large granular lymphocytic leukemia identifies BCL11B as a potential biomarker
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9664638
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9664638
Other Identifiers
ISSN
1868-7075,1868-7083
E-ISSN
1868-7083,1868-7075
DOI
10.1186/s13148-022-01362-z
