Extracellular mitochondria drive CD8 T cell dysfunction in trauma by upregulating CD39
Extracellular mitochondria drive CD8 T cell dysfunction in trauma by upregulating CD39
About this item
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Author / Creator
Publisher
England: BMJ Publishing Group Ltd and British Thoracic Society
Journal title
Language
English
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Publication information
Publisher
England: BMJ Publishing Group Ltd and British Thoracic Society
Subjects
More information
Scope and Contents
Contents
RationaleThe increased mortality and morbidity seen in critically injured patients appears associated with systemic inflammatory response syndrome (SIRS) and immune dysfunction, which ultimately predisposes to infection. Mitochondria released by injury could generate danger molecules, for example, ATP, which in turn would be rapidly scavenged by ec...
Alternative Titles
Full title
Extracellular mitochondria drive CD8 T cell dysfunction in trauma by upregulating CD39
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9691787
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9691787
Other Identifiers
ISSN
0040-6376,1468-3296
E-ISSN
1468-3296
DOI
10.1136/thoraxjnl-2021-218047
