PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modula...
PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment
About this item
Full title
Author / Creator
Missiroli, Sonia , Perrone, Mariasole , Gafà, Roberta , Nicoli, Francesco , Bonora, Massimo , Morciano, Giampaolo , Boncompagni, Caterina , Marchi, Saverio , Lebiedzinska-Arciszewska, Magdalena , Vezzani, Bianca , Lanza, Giovanni , Kricek, Franz , Borghi, Alessandro , Fiorica, Francesco , Ito, Keisuke , Wieckowski, Mariusz R. , Di Virgilio, Francesco , Abelli, Luigi , Pinton, Paolo and Giorgi, Carlotta
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Uncontrolled inflammatory response arising from the tumor microenvironment (TME) significantly contributes to cancer progression, prompting an investigation and careful evaluation of counter-regulatory mechanisms. We identified a trimeric complex at the mitochondria-associated membranes (MAMs), in which the purinergic P2X7 receptor - NLRP3 inflamma...
Alternative Titles
Full title
PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment
Authors, Artists and Contributors
Author / Creator
Perrone, Mariasole
Gafà, Roberta
Nicoli, Francesco
Bonora, Massimo
Morciano, Giampaolo
Boncompagni, Caterina
Marchi, Saverio
Lebiedzinska-Arciszewska, Magdalena
Vezzani, Bianca
Lanza, Giovanni
Kricek, Franz
Borghi, Alessandro
Fiorica, Francesco
Ito, Keisuke
Wieckowski, Mariusz R.
Di Virgilio, Francesco
Abelli, Luigi
Pinton, Paolo
Giorgi, Carlotta
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9713080
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9713080
Other Identifiers
ISSN
1350-9047,1476-5403
E-ISSN
1476-5403
DOI
10.1038/s41418-022-01095-9
