Enhancement of recombinant human IL-24 (rhIL-24) protein production from site-specific integrated en...
Enhancement of recombinant human IL-24 (rhIL-24) protein production from site-specific integrated engineered CHO cells by sodium butyrate treatment
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Author / Creator
Hua, Jilei , Xu, Hanli , Zhang, Yao , Ge, Jianlin , Liu, Mengzhe , Wang, Yuqi , Wei, Yuexian , Shi, Yinan , Hou, LingLing and Jiang, Hong
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Scope and Contents
Contents
Interleukin-24 (IL-24) has specific inhibitory effects on the proliferation of various tumor cells with almost no toxicity to normal cells. The antitumor activity of recombinant human IL-24 protein produced in mammalian cells is much higher than that of bacteria, but its expression level is extremely low. Sodium butyrate (NaBu) was utilized as a me...
Alternative Titles
Full title
Enhancement of recombinant human IL-24 (rhIL-24) protein production from site-specific integrated engineered CHO cells by sodium butyrate treatment
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9719890
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9719890
Other Identifiers
ISSN
1615-7591
E-ISSN
1615-7605
DOI
10.1007/s00449-022-02801-0