The Mechanism of Selective Recognition of Lipid Substrate by hDHHC20 Enzyme
The Mechanism of Selective Recognition of Lipid Substrate by hDHHC20 Enzyme
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Publisher
Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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Contents
S-acylation is a post-translational linkage of long chain fatty acids to cysteines, playing a key role in normal physiology and disease. In human cells, the reaction is catalyzed by a family of 23 membrane DHHC-acyltransferases (carrying an Asp-His-His-Cys catalytic motif) in two stages: (1) acyl-CoA-mediated autoacylation of the enzyme; and (2) fu...
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Full title
The Mechanism of Selective Recognition of Lipid Substrate by hDHHC20 Enzyme
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9739150
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9739150
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms232314791
