Synthon-based ligand discovery in virtual libraries of over 11 billion compounds
Synthon-based ligand discovery in virtual libraries of over 11 billion compounds
About this item
Full title
Author / Creator
Sadybekov, Arman A. , Sadybekov, Anastasiia V. , Liu, Yongfeng , Iliopoulos-Tsoutsouvas, Christos , Huang, Xi-Ping , Pickett, Julie , Houser, Blake , Patel, Nilkanth , Tran, Ngan K. , Tong, Fei , Zvonok, Nikolai , Jain, Manish K. , Savych, Olena , Radchenko, Dmytro S. , Nikas, Spyros P. , Petasis, Nicos A. , Moroz, Yurii S. , Roth, Bryan L. , Makriyannis, Alexandros and Katritch, Vsevolod
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Structure-based virtual ligand screening is emerging as a key paradigm for early drug discovery owing to the availability of high-resolution target structures
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–
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and ultra-large libraries of virtual compounds
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,
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. However, to keep pace with the rapid growth of virtual libraries, such as readily available for synthesis...
Alternative Titles
Full title
Synthon-based ligand discovery in virtual libraries of over 11 billion compounds
Authors, Artists and Contributors
Author / Creator
Sadybekov, Anastasiia V.
Liu, Yongfeng
Iliopoulos-Tsoutsouvas, Christos
Huang, Xi-Ping
Pickett, Julie
Houser, Blake
Patel, Nilkanth
Tran, Ngan K.
Tong, Fei
Zvonok, Nikolai
Jain, Manish K.
Savych, Olena
Radchenko, Dmytro S.
Nikas, Spyros P.
Petasis, Nicos A.
Moroz, Yurii S.
Roth, Bryan L.
Makriyannis, Alexandros
Katritch, Vsevolod
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9763054
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9763054
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-021-04220-9
