Caffeine treatment started before injury reduces hypoxic–ischemic white-matter damage in neonatal ra...
Caffeine treatment started before injury reduces hypoxic–ischemic white-matter damage in neonatal rats by regulating phenotypic microglia polarization
About this item
Full title
Author / Creator
Yang, Liu , Yu, Xuefei , Zhang, Yajun , Liu, Na , Xue, Xindong and Fu, Jianhua
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Background
Reducing neuroinflammatory damage is an effective strategy for treating white-matter damage (WMD) in premature infants. Caffeine can ameliorate hypoxia–ischemia-induced brain WMD; however, its neuroprotective effect and mechanism against hypoxic–ischemic WMD remain unclear.
Methods
We used 3-day-old Sprague–Dawley rats to establ...
Alternative Titles
Full title
Caffeine treatment started before injury reduces hypoxic–ischemic white-matter damage in neonatal rats by regulating phenotypic microglia polarization
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9771815
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9771815
Other Identifiers
ISSN
0031-3998
E-ISSN
1530-0447
DOI
10.1038/s41390-021-01924-6
