Targeted Methylation Profiling of Single Laser-Capture Microdissected Post-Mortem Brain Cells by Ada...
Targeted Methylation Profiling of Single Laser-Capture Microdissected Post-Mortem Brain Cells by Adapted Limiting Dilution Bisulfite Pyrosequencing (LDBSP)
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Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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A reoccurring issue in neuroepigenomic studies, especially in the context of neurodegenerative disease, is the use of (heterogeneous) bulk tissue, which generates noise during epigenetic profiling. A workable solution to this issue is to quantify epigenetic patterns in individually isolated neuronal cells using laser capture microdissection (LCM)....
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Full title
Targeted Methylation Profiling of Single Laser-Capture Microdissected Post-Mortem Brain Cells by Adapted Limiting Dilution Bisulfite Pyrosequencing (LDBSP)
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9779089
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9779089
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms232415571
