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Substrate Recognition Properties from an Intermediate Structural State of the UreA Transporter

Substrate Recognition Properties from an Intermediate Structural State of the UreA Transporter

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9783183

Substrate Recognition Properties from an Intermediate Structural State of the UreA Transporter

About this item

Full title

Substrate Recognition Properties from an Intermediate Structural State of the UreA Transporter

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2022-12, Vol.23 (24), p.16039

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Through a combination of comparative modeling, site-directed and classical random mutagenesis approaches, we previously identified critical residues for binding, recognition, and translocation of urea, and its inhibition by 2-thiourea and acetamide in the Aspergillus nidulans urea transporter, UreA. To deepen the structural characterization of UreA...

Alternative Titles

Full title

Substrate Recognition Properties from an Intermediate Structural State of the UreA Transporter

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9783183

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9783183

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms232416039

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