Paricalcitol Improves the Angiopoietin/Tie-2 and VEGF/VEGFR2 Signaling Pathways in Adriamycin-Induce...
Paricalcitol Improves the Angiopoietin/Tie-2 and VEGF/VEGFR2 Signaling Pathways in Adriamycin-Induced Nephropathy
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Author / Creator
Deluque, Amanda Lima , Oliveira, Beatriz Magalhães , Souza, Cláudia Silva , Maciel, Ana Lívia Dias , Francescato, Heloísa Della Coletta , Giovanini, Cleonice , de Almeida, Lucas Ferreira , de Paula, Francisco José Albuquerque , Costa, Roberto Silva , Antunes-Rodrigues, José and Coimbra, Terezila Machado
Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Renal endothelial cell (EC) injury and microvascular dysfunction contribute to chronic kidney disease (CKD). In recent years, increasing evidence has suggested that EC undergoes an endothelial-to-mesenchymal transition (EndoMT), which might promote fibrosis. Adriamycin (ADR) induces glomerular endothelial dysfunction, which leads to progressive pro...
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Full title
Paricalcitol Improves the Angiopoietin/Tie-2 and VEGF/VEGFR2 Signaling Pathways in Adriamycin-Induced Nephropathy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9783872
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9783872
Other Identifiers
ISSN
2072-6643
E-ISSN
2072-6643
DOI
10.3390/nu14245316