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Rap1 regulates apical contractility to allow embryonic morphogenesis without tissue disruption and a...

Rap1 regulates apical contractility to allow embryonic morphogenesis without tissue disruption and a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9816648

Rap1 regulates apical contractility to allow embryonic morphogenesis without tissue disruption and acts in part via Canoe-independent mechanisms

About this item

Full title

Rap1 regulates apical contractility to allow embryonic morphogenesis without tissue disruption and acts in part via Canoe-independent mechanisms

Publisher

United States: The American Society for Cell Biology

Journal title

Molecular biology of the cell, 2023-01, Vol.34 (1), p.ar7

Language

English

Formats

Publication information

Publisher

United States: The American Society for Cell Biology

More information

Scope and Contents

Contents

Embryonic morphogenesis is powered by dramatic changes in cell shape and arrangement driven by the cytoskeleton and its connections to adherens junctions. This requires robust linkage allowing morphogenesis without disrupting tissue integrity. The small GTPase Rap1 is a key regulator of cell adhesion, controlling both cadherin-mediated and integrin...

Alternative Titles

Full title

Rap1 regulates apical contractility to allow embryonic morphogenesis without tissue disruption and acts in part via Canoe-independent mechanisms

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9816648

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9816648

Other Identifiers

ISSN

1059-1524,1939-4586

E-ISSN

1939-4586

DOI

10.1091/mbc.E22-05-0176

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