Rap1 regulates apical contractility to allow embryonic morphogenesis without tissue disruption and a...
Rap1 regulates apical contractility to allow embryonic morphogenesis without tissue disruption and acts in part via Canoe-independent mechanisms
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Publisher
United States: The American Society for Cell Biology
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Language
English
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Publisher
United States: The American Society for Cell Biology
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Contents
Embryonic morphogenesis is powered by dramatic changes in cell shape and arrangement, driven by the cytoskeleton connected to adherens junctions. The role of the small GTPase Rap1 and its GEF Dizzy is explored, using Drosophila as a model. Rap1 regulates apical contractility and epithelial integrity, using Canoe and additional effectors.
Embryon...
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Full title
Rap1 regulates apical contractility to allow embryonic morphogenesis without tissue disruption and acts in part via Canoe-independent mechanisms
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9816648
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9816648
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ISSN
1059-1524,1939-4586
E-ISSN
1939-4586
DOI
10.1091/mbc.E22-05-0176