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Allopregnanolone: Metabolism, Mechanisms of Action, and Its Role in Cancer

Allopregnanolone: Metabolism, Mechanisms of Action, and Its Role in Cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9820109

Allopregnanolone: Metabolism, Mechanisms of Action, and Its Role in Cancer

About this item

Full title

Allopregnanolone: Metabolism, Mechanisms of Action, and Its Role in Cancer

Publisher

Switzerland: MDPI

Journal title

International journal of molecular sciences, 2022-12, Vol.24 (1), p.560

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI

More information

Scope and Contents

Contents

Allopregnanolone (3α-THP) has been one of the most studied progesterone metabolites for decades. 3α-THP and its synthetic analogs have been evaluated as therapeutic agents for pathologies such as anxiety and depression. Enzymes involved in the metabolism of 3α-THP are expressed in classical and nonclassical steroidogenic tissues. Additionally, due...

Alternative Titles

Full title

Allopregnanolone: Metabolism, Mechanisms of Action, and Its Role in Cancer

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9820109

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9820109

Other Identifiers

ISSN

1422-0067

E-ISSN

1422-0067

DOI

10.3390/ijms24010560

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