Microglia ferroptosis is regulated by SEC24B and contributes to neurodegeneration
Microglia ferroptosis is regulated by SEC24B and contributes to neurodegeneration
About this item
Full title
Author / Creator
Ryan, Sean K. , Zelic, Matija , Han, Yingnan , Teeple, Erin , Chen, Luoman , Sadeghi, Mahdiar , Shankara, Srinivas , Guo, Lilu , Li, Cong , Pontarelli, Fabrizio , Jensen, Elizabeth H. , Comer, Ashley L. , Kumar, Dinesh , Zhang, Mindy , Gans, Joseph , Zhang, Bailin , Proto, Jonathan D. , Saleh, Jacqueline , Dodge, James C. , Savova, Virginia , Rajpal, Deepak , Ofengeim, Dimitry and Hammond, Timothy R.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Iron dysregulation has been implicated in multiple neurodegenerative diseases, including Parkinson’s disease (PD). Iron-loaded microglia are frequently found in affected brain regions, but how iron accumulation influences microglia physiology and contributes to neurodegeneration is poorly understood. Here we show that human induced pluripotent stem...
Alternative Titles
Full title
Microglia ferroptosis is regulated by SEC24B and contributes to neurodegeneration
Authors, Artists and Contributors
Author / Creator
Zelic, Matija
Han, Yingnan
Teeple, Erin
Chen, Luoman
Sadeghi, Mahdiar
Shankara, Srinivas
Guo, Lilu
Li, Cong
Pontarelli, Fabrizio
Jensen, Elizabeth H.
Comer, Ashley L.
Kumar, Dinesh
Zhang, Mindy
Gans, Joseph
Zhang, Bailin
Proto, Jonathan D.
Saleh, Jacqueline
Dodge, James C.
Savova, Virginia
Rajpal, Deepak
Ofengeim, Dimitry
Hammond, Timothy R.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9829540
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9829540
Other Identifiers
ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/s41593-022-01221-3
