CCL18 signaling from tumor-associated macrophages activates fibroblasts to adopt a chemoresistance-i...
CCL18 signaling from tumor-associated macrophages activates fibroblasts to adopt a chemoresistance-inducing phenotype
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Author / Creator
Zeng, Wenfeng , Xiong, Lixiong , Wu, Wei , Li, Shunrong , Liu, Jiang , Yang, Linbing , Lao, Liyan , Huang, Penghan , Zhang, Mengmeng , Chen, Huiping , Miao, Nanyan , Lin, Zhirong , Liu, Zifei , Yang, Xinyu , Wang, Jiayi , Wang, Pei , Song, Erwei , Yao, Yandan , Nie, Yan , Chen, Jianing and Huang, Di
Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
The heterogeneity of cancer-associated fibroblasts (CAFs) might be ascribed to differences in origin. CD10 and GPR77 have been reported to identify a chemoresistance-inducing CAF subset in breast cancer. However, the precise mechanism for the formation of the CD10
+
GPR77
+
CAFs remains unknown. In this study, we found that CCL18 expres...
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Full title
CCL18 signaling from tumor-associated macrophages activates fibroblasts to adopt a chemoresistance-inducing phenotype
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9836934
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9836934
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-022-02540-2