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Serum amyloid P component (SAP) modulates antidepressant effects through promoting membrane insertio...

Serum amyloid P component (SAP) modulates antidepressant effects through promoting membrane insertio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9852251

Serum amyloid P component (SAP) modulates antidepressant effects through promoting membrane insertion of the serotonin transporter

About this item

Full title

Serum amyloid P component (SAP) modulates antidepressant effects through promoting membrane insertion of the serotonin transporter

Publisher

England: Nature Publishing Group

Journal title

Neuropsychopharmacology (New York, N.Y.), 2023-02, Vol.48 (3), p.508-517

Language

English

Formats

Publication information

Publisher

England: Nature Publishing Group

More information

Scope and Contents

Contents

Serum amyloid P component (SAP) is a universal constituent of human amyloid deposits including those in Alzheimer's disease. SAP has been observed to be elevated in patients with depression, and higher SAP levels are associated with better response to the antidepressant escitalopram. The mechanisms underlying these clinical observations remain uncl...

Alternative Titles

Full title

Serum amyloid P component (SAP) modulates antidepressant effects through promoting membrane insertion of the serotonin transporter

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9852251

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9852251

Other Identifiers

ISSN

0893-133X

E-ISSN

1740-634X

DOI

10.1038/s41386-022-01449-4

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