Neutralizing antibody correlates of sequence specific dengue disease in a tetravalent dengue vaccine...
Neutralizing antibody correlates of sequence specific dengue disease in a tetravalent dengue vaccine efficacy trial in Asia
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Publisher
Netherlands: Elsevier Limited
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Language
English
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Publisher
Netherlands: Elsevier Limited
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Contents
Highlights•This correlates analysis integrated host immune response & pathogen sequence data. •The nAb correlate of risk depends on dengue sequence in baseline seropositive participants. •Dependency of correlates on sequence-distance stronger in the vaccine (vs placebo) arm. •Infection- vs vaccine-induced nAbs may affect dengue risk differently. •n...
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Full title
Neutralizing antibody correlates of sequence specific dengue disease in a tetravalent dengue vaccine efficacy trial in Asia
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9881745
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9881745
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ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2022.08.055