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Structural basis of lipopolysaccharide maturation by the O-antigen ligase

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Structural basis of lipopolysaccharide maturation by the O-antigen ligase

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9884178

Structural basis of lipopolysaccharide maturation by the O-antigen ligase

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Publisher

London: Nature Publishing Group UK

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Contents

The outer membrane of Gram-negative bacteria has an external leaflet that is largely composed of lipopolysaccharide, which provides a selective permeation barrier, particularly against antimicrobials
1
. The final and crucial step in the biosynthesis of lipopolysaccharide is the addition of a species-dependent O-antigen to the lipid A core ol...

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Full title

Structural basis of lipopolysaccharide maturation by the O-antigen ligase

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Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9884178

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9884178

Other Identifiers

ISSN

0028-0836,1476-4687

E-ISSN

1476-4687

DOI

10.1038/s41586-022-04555-x

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