PU.1 promotes development of rheumatoid arthritis via repressing FLT3 in macrophages and fibroblast-...
PU.1 promotes development of rheumatoid arthritis via repressing FLT3 in macrophages and fibroblast-like synoviocytes
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Author / Creator
Tu, Jiajie , Chen, Weile , Fang, Yilong , Han, Dafei , Chen, Yizhao , Jiang, Haifeng , Tan, Xuewen , Xu, Zhen , Wu, Xuming , Wang, Huihui , Zhu, Xiangling , Hong, Wenming , Li, Zhenbao , Zhu, Chen , Wang, Xinming and Wei, Wei
Publisher
England: BMJ Publishing Group Ltd and European League Against Rheumatism
Journal title
Language
English
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Publication information
Publisher
England: BMJ Publishing Group Ltd and European League Against Rheumatism
Subjects
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Scope and Contents
Contents
ObjectivesTo uncover the function and underlying mechanism of an essential transcriptional factor, PU.1, in the development of rheumatoid arthritis (RA).MethodsThe expression and localisation of PU.1 and its potential target, FMS-like tyrosine kinase 3 (FLT3), in the synovium of patients with RA were determined by western blot and immunohistochemic...
Alternative Titles
Full title
PU.1 promotes development of rheumatoid arthritis via repressing FLT3 in macrophages and fibroblast-like synoviocytes
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9887374
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9887374
Other Identifiers
ISSN
0003-4967
E-ISSN
1468-2060
DOI
10.1136/ard-2022-222708