Proteolytic cleavage of membrane proteins by membrane type‐1 MMP regulates cancer malignant progress...
Proteolytic cleavage of membrane proteins by membrane type‐1 MMP regulates cancer malignant progression
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Author / Creator
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
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Publisher
England: John Wiley & Sons, Inc
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Scope and Contents
Contents
Strategies to develop cancer therapies using inhibitors that target matrix metalloproteinases (MMPs), particularly membrane type‐1 MMP (MT1‐MMP), have failed. This is predominantly attributed to the specificity of MMP inhibitors and numerous functions of MMPs; therefore, targeting substrates with such broad specificity can lead to off‐target effect...
Alternative Titles
Full title
Proteolytic cleavage of membrane proteins by membrane type‐1 MMP regulates cancer malignant progression
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9899627
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9899627
Other Identifiers
ISSN
1347-9032
E-ISSN
1349-7006
DOI
10.1111/cas.15638