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Extensive metabolic consequences of human glycosyltransferase gene knockouts in prostate cancer

Extensive metabolic consequences of human glycosyltransferase gene knockouts in prostate cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9902621

Extensive metabolic consequences of human glycosyltransferase gene knockouts in prostate cancer

About this item

Full title

Extensive metabolic consequences of human glycosyltransferase gene knockouts in prostate cancer

Publisher

London: Nature Publishing Group UK

Journal title

British journal of cancer, 2023-01, Vol.128 (2), p.285-296

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Background
Naturally occurring germline gene deletions (KO) represent a unique setting to interrogate gene functions. Complete deletions and differential expression of the human glycosyltransferase
UGT2B17
and
UGT2B28
genes are linked to prostate cancer (PCa) risk and progression, leukaemia, autoimmune and other diseases.
Methods<...

Alternative Titles

Full title

Extensive metabolic consequences of human glycosyltransferase gene knockouts in prostate cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9902621

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9902621

Other Identifiers

ISSN

0007-0920

E-ISSN

1532-1827

DOI

10.1038/s41416-022-02040-w

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