A genome-scale screen for synthetic drivers of T cell proliferation
A genome-scale screen for synthetic drivers of T cell proliferation
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
The engineering of autologous patient T cells for adoptive cell therapies has revolutionized the treatment of several types of cancer
1
. However, further improvements are needed to increase response and cure rates. CRISPR-based loss-of-function screens have been limited to negative regulators of T cell functions
2
–
4
and raise s...
Alternative Titles
Full title
A genome-scale screen for synthetic drivers of T cell proliferation
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9908437
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9908437
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-022-04494-7
