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Xanthine dehydrogenase rewires metabolism and the survival of nutrient deprived lung adenocarcinoma...

Xanthine dehydrogenase rewires metabolism and the survival of nutrient deprived lung adenocarcinoma...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9909990

Xanthine dehydrogenase rewires metabolism and the survival of nutrient deprived lung adenocarcinoma cells by facilitating UPR and autophagic degradation

About this item

Full title

Xanthine dehydrogenase rewires metabolism and the survival of nutrient deprived lung adenocarcinoma cells by facilitating UPR and autophagic degradation

Publisher

Australia: Ivyspring International Publisher Pty Ltd

Journal title

International journal of biological sciences, 2023, Vol.19 (3), p.772-788

Language

English

Formats

Publication information

Publisher

Australia: Ivyspring International Publisher Pty Ltd

More information

Scope and Contents

Contents

Xanthine dehydrogenase (XDH) is the rate-limiting enzyme in purine catabolism by converting hypoxanthine to xanthine and xanthine to uric acid. The altered expression and activity of XDH are associated with the development and prognosis of multiple types of cancer, while its role in lung adenocarcinoma (LUAD) remains unknown. Herein, we demonstrate...

Alternative Titles

Full title

Xanthine dehydrogenase rewires metabolism and the survival of nutrient deprived lung adenocarcinoma cells by facilitating UPR and autophagic degradation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9909990

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9909990

Other Identifiers

ISSN

1449-2288

E-ISSN

1449-2288

DOI

10.7150/ijbs.78948

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