Xanthine dehydrogenase rewires metabolism and the survival of nutrient deprived lung adenocarcinoma...
Xanthine dehydrogenase rewires metabolism and the survival of nutrient deprived lung adenocarcinoma cells by facilitating UPR and autophagic degradation
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Author / Creator
Chen, Man-man , Guo, Wei , Chen, Si-meng , Guo, Xiao-zhen , Xu, Lan , Ma, Xiao-yu , Wang, Yu-xiang , Xie, Cen and Meng, Ling-hua
Publisher
Australia: Ivyspring International Publisher Pty Ltd
Journal title
Language
English
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Publication information
Publisher
Australia: Ivyspring International Publisher Pty Ltd
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Scope and Contents
Contents
Xanthine dehydrogenase (XDH) is the rate-limiting enzyme in purine catabolism by converting hypoxanthine to xanthine and xanthine to uric acid. The altered expression and activity of XDH are associated with the development and prognosis of multiple types of cancer, while its role in lung adenocarcinoma (LUAD) remains unknown. Herein, we demonstrate...
Alternative Titles
Full title
Xanthine dehydrogenase rewires metabolism and the survival of nutrient deprived lung adenocarcinoma cells by facilitating UPR and autophagic degradation
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9909990
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9909990
Other Identifiers
ISSN
1449-2288
E-ISSN
1449-2288
DOI
10.7150/ijbs.78948