Simvastatin Reduces NETosis to Attenuate Severe Asthma by Inhibiting PAD4 Expression
Simvastatin Reduces NETosis to Attenuate Severe Asthma by Inhibiting PAD4 Expression
About this item
Full title
Author / Creator
Chen, Yun-Rong , Xiang, Xu-Dong , Sun, Fei , Xiao, Bo-Wen , Yan, Mu-Yun , Peng, Biao and Liu, Da
Publisher
United States: Hindawi
Journal title
Language
English
Formats
Publication information
Publisher
United States: Hindawi
Subjects
More information
Scope and Contents
Contents
Objective. Patients with severe asthma respond poorly to corticosteroids, and their care accounts for more than 60% of the total costs attributed to asthma. Neutrophils form neutrophil extracellular traps (NETs), which play a crucial role in severe asthma. Statins have shown anti-inflammatory effects by reducing NETosis. In this study, we investiga...
Alternative Titles
Full title
Simvastatin Reduces NETosis to Attenuate Severe Asthma by Inhibiting PAD4 Expression
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9911252
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9911252
Other Identifiers
ISSN
1942-0900
E-ISSN
1942-0994
DOI
10.1155/2023/1493684
