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Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE

Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9945843

Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE

About this item

Full title

Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2023-02, Vol.614 (7948), p.530-538

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Resident-tissue macrophages (RTMs) arise from embryonic precursors
1
,
2
, yet the developmental signals that shape their longevity remain largely unknown. Here we demonstrate in mice genetically deficient in 12-lipoxygenase and 15-lipoxygenase (
Alox15
−/−
mice) that neonatal neutrophil-derived 12-HETE is required for self-ren...

Alternative Titles

Full title

Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9945843

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9945843

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-022-05660-7

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