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A NPAS4–NuA4 complex couples synaptic activity to DNA repair

A NPAS4–NuA4 complex couples synaptic activity to DNA repair

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9946837

A NPAS4–NuA4 complex couples synaptic activity to DNA repair

About this item

Full title

A NPAS4–NuA4 complex couples synaptic activity to DNA repair

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2023-02, Vol.614 (7949), p.732-741

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Neuronal activity is crucial for adaptive circuit remodelling but poses an inherent risk to the stability of the genome across the long lifespan of postmitotic neurons
1

5
. Whether neurons have acquired specialized genome protection mechanisms that enable them to withstand decades of potentially damaging stimuli during periods of hei...

Alternative Titles

Full title

A NPAS4–NuA4 complex couples synaptic activity to DNA repair

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9946837

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9946837

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-023-05711-7

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