Mispatterning and interneuron deficit in Tourette Syndrome basal ganglia organoids
Mispatterning and interneuron deficit in Tourette Syndrome basal ganglia organoids
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Tourette Syndrome (TS) is a neuropsychiatric disorder thought to involve a reduction of basal ganglia (BG) interneurons and malfunctioning of the BG circuitry. However, whether interneurons fail to develop or are lost postnatally remains unknown. To investigate the pathophysiology of early development in TS, induced pluripotent stem cell (iPSC)-der...
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Full title
Mispatterning and interneuron deficit in Tourette Syndrome basal ganglia organoids
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9949887
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9949887
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ISSN
1359-4184
E-ISSN
1476-5578
DOI
10.1038/s41380-022-01880-5
