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Caspase Inhibition Modulates Monocyte-Derived Macrophage Polarization in Damaged Tissues

Caspase Inhibition Modulates Monocyte-Derived Macrophage Polarization in Damaged Tissues

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9964254

Caspase Inhibition Modulates Monocyte-Derived Macrophage Polarization in Damaged Tissues

About this item

Full title

Caspase Inhibition Modulates Monocyte-Derived Macrophage Polarization in Damaged Tissues

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2023-02, Vol.24 (4), p.4151

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Circulating monocytes are recruited in damaged tissues to generate macrophages that modulate disease progression. Colony-stimulating factor-1 (CSF-1) promotes the generation of monocyte-derived macrophages, which involves caspase activation. Here, we demonstrate that activated caspase-3 and caspase-7 are located to the vicinity of the mitochondria...

Alternative Titles

Full title

Caspase Inhibition Modulates Monocyte-Derived Macrophage Polarization in Damaged Tissues

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9964254

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9964254

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms24044151

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