The Relationship between Iron and LRRK2 in a 6-OHDA-Induced Parkinson’s Disease Model
The Relationship between Iron and LRRK2 in a 6-OHDA-Induced Parkinson’s Disease Model
About this item
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Author / Creator
Jia, Ruru , Liu, Yanling , Shuai, Ke , Zhou, Cheng , Chen, Lei , Zhu, Li and Wu, Xiao-Mei
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publication information
Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
The pathogenesis of Parkinson’s disease (PD) is very complex and still needs further exploration. Leucine-rich repeat kinase 2 (LRRK2) is associated with familial PD in mutant forms and sporadic PD in the wild-type form. Abnormal iron accumulation is found in the substantia nigra of PD patients, but its exact effects are not very clear. Here, we sh...
Alternative Titles
Full title
The Relationship between Iron and LRRK2 in a 6-OHDA-Induced Parkinson’s Disease Model
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9964371
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9964371
Other Identifiers
ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms24043709