General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine...
General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Taf4 (TATA-box binding protein-associated factor 4) is a subunit of the general transcription factor TFIID, a component of the RNA polymerase II pre-initiation complex that interacts with tissue-specific transcription factors to regulate gene expression. Properly regulated gene expression is particularly important in the intestinal epithelium that...
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Full title
General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9984434
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9984434
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ISSN
1350-9047,1476-5403
E-ISSN
1476-5403
DOI
10.1038/s41418-022-01109-6
