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Immune-mediated myogenesis and acetylcholine receptor clustering promote a slow disease progression...

Immune-mediated myogenesis and acetylcholine receptor clustering promote a slow disease progression...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9996869

Immune-mediated myogenesis and acetylcholine receptor clustering promote a slow disease progression in ALS mouse models

About this item

Full title

Immune-mediated myogenesis and acetylcholine receptor clustering promote a slow disease progression in ALS mouse models

Publisher

England: Springer

Journal title

Inflammation and Regeneration, 2023-03, Vol.43 (1), p.19-19

Language

English

Formats

Publication information

Publisher

England: Springer

More information

Scope and Contents

Contents

Amyotrophic lateral sclerosis (ALS) is a heterogeneous disease in terms of onset and progression rate. This may account for therapeutic clinical trial failure. Transgenic SOD1G93A mice on C57 or 129Sv background have a slow and fast disease progression rate, mimicking the variability observed in patients. Based on evidence inferring the active infl...

Alternative Titles

Full title

Immune-mediated myogenesis and acetylcholine receptor clustering promote a slow disease progression in ALS mouse models

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9996869

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9996869

Other Identifiers

ISSN

1880-9693

E-ISSN

1880-8190

DOI

10.1186/s41232-023-00270-w

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