In papillary thyroid carcinoma, TIMP-1 expression correlates with BRAFV600E mutation status and toge...
In papillary thyroid carcinoma, TIMP-1 expression correlates with BRAFV600E mutation status and together with hypoxia-related proteins predicts aggressive behavior
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Contents
BRAF
V600E
causes upregulation of tissue inhibitor of metalloproteinase-1 (TIMP-1), which promotes cell invasion in papillary thyroid carcinoma (PTC). Hypoxia-inducible factor-1α (HIF-1α) is regulated by hypoxia and also by the
BRAF
-mediated signaling pathway in PTC. We assessed the association of expression of TIMP-1, HIF-1α, and hypo...
Alternative Titles
Full title
In papillary thyroid carcinoma, TIMP-1 expression correlates with BRAFV600E mutation status and together with hypoxia-related proteins predicts aggressive behavior
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Record Identifier
TN_cdi_springer_journals_10_1007_s00428_013_1453_x
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_springer_journals_10_1007_s00428_013_1453_x
Other Identifiers
ISSN
0945-6317
E-ISSN
1432-2307
DOI
10.1007/s00428-013-1453-x
