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Complement C3 From Astrocytes Plays Significant Roles in Sustained Activation of Microglia and Cogni...

Complement C3 From Astrocytes Plays Significant Roles in Sustained Activation of Microglia and Cogni...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_springer_journals_10_1007_s11481_024_10107_z

Complement C3 From Astrocytes Plays Significant Roles in Sustained Activation of Microglia and Cognitive Dysfunctions Triggered by Systemic Inflammation After Laparotomy in Adult Male Mice: C3 Mediated Microglial Activation and Cognitive Dysfunction

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Full title

Complement C3 From Astrocytes Plays Significant Roles in Sustained Activation of Microglia and Cognitive Dysfunctions Triggered by Systemic Inflammation After Laparotomy in Adult Male Mice: C3 Mediated Microglial Activation and Cognitive Dysfunction

Publisher

New York: Springer US

Journal title

Journal of neuroimmune pharmacology, 2024-03, Vol.19 (1)

Language

English

Formats

Publication information

Publisher

New York: Springer US

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Scope and Contents

Contents

Aberrant activation of complement cascades plays an important role in the progress of neurological disorders. Complement C3, the central complement component, has been implicated in synaptic loss and cognitive impairment. Recent study has shown that wound injury-induced systemic inflammation can trigger the increase of C3 in the brain. Our previous...

Alternative Titles

Full title

Complement C3 From Astrocytes Plays Significant Roles in Sustained Activation of Microglia and Cognitive Dysfunctions Triggered by Systemic Inflammation After Laparotomy in Adult Male Mice: C3 Mediated Microglial Activation and Cognitive Dysfunction

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Primary Identifiers

Record Identifier

TN_cdi_springer_journals_10_1007_s11481_024_10107_z

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_springer_journals_10_1007_s11481_024_10107_z

Other Identifiers

E-ISSN

1557-1904

DOI

10.1007/s11481-024-10107-z

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