Combination of broad molecular screening and cytogenetic analysis for genetic risk assignment and di...
Combination of broad molecular screening and cytogenetic analysis for genetic risk assignment and diagnosis in patients with acute leukemia: Acute Leukemias
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Author / Creator
Meyer-Monard, S , Parlier, V , Passweg, J , Mühlematter, D , Hess, U , Bargetzi, M , Kühne, T , Cabrol, C , Gratwohl, A , Jotterand, M and Tichelli, A
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
We evaluated the impact of genetic analysis combining cytogenetics and broad molecular screening on leukemia diagnosis according to World Health Organization (WHO) and on genetic risk assignment. A two-step nested multiplex RT–PCR assay was used that allowed the detection of 29 fusion transcripts. A total of 186 patients (104 males (56%), 174 adult...
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Full title
Combination of broad molecular screening and cytogenetic analysis for genetic risk assignment and diagnosis in patients with acute leukemia: Acute Leukemias
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Record Identifier
TN_cdi_springer_journals_10_1038_sj_leu_2404044
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_springer_journals_10_1038_sj_leu_2404044
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/sj.leu.2404044
