Neurochemical, Electrophysiological and Pharmacological Profiles of the Selective Inhibitor of the G...
Neurochemical, Electrophysiological and Pharmacological Profiles of the Selective Inhibitor of the Glycine Transporter-1 SSR504734, a Potential New Type of Antipsychotic: Preclinical Research
About this item
Full title
Author / Creator
Depoortère, Ronan , Dargazanli, Gihad , Estenne-Bouhtou, Genevieve , Coste, Annick , Lanneau, Christophe , Desvignes, Christophe , Poncelet, Martine , Heaulme, Michel , Santucci, Vincent , Decobert, Michel , Cudennec, Annie , Voltz, Carolle , Boulay, Denis , Paul Terranova, Jean , Stemmelin, Jeanne , Roger, Pierre , Marabout, Benoit , Sevrin, Mireille , Vigé, Xavier , Biton, Bruno , Steinberg, Régis , Françon, Dominique , Alonso, Richard , Avenet, Patrick , Oury-Donat, Florence , Perrault, Ghislaine , Griebel, Guy , George, Pascal , Soubrié, Philippe and Scatton, Bernard
Publisher
Cham: Springer International Publishing
Journal title
Language
English
Formats
Publication information
Publisher
Cham: Springer International Publishing
Subjects
More information
Scope and Contents
Contents
Noncompetitive
N
-methyl-
D
-aspartate (NMDA) blockers induce schizophrenic-like symptoms in humans, presumably by impairing glutamatergic transmission. Therefore, a compound potentiating this neurotransmission, by increasing extracellular levels of glycine (a requisite co-agonist of glutamate), could possess antipsychotic activity. Blo...
Alternative Titles
Full title
Neurochemical, Electrophysiological and Pharmacological Profiles of the Selective Inhibitor of the Glycine Transporter-1 SSR504734, a Potential New Type of Antipsychotic: Preclinical Research
Authors, Artists and Contributors
Author / Creator
Dargazanli, Gihad
Estenne-Bouhtou, Genevieve
Coste, Annick
Lanneau, Christophe
Desvignes, Christophe
Poncelet, Martine
Heaulme, Michel
Santucci, Vincent
Decobert, Michel
Cudennec, Annie
Voltz, Carolle
Boulay, Denis
Paul Terranova, Jean
Stemmelin, Jeanne
Roger, Pierre
Marabout, Benoit
Sevrin, Mireille
Vigé, Xavier
Biton, Bruno
Steinberg, Régis
Françon, Dominique
Alonso, Richard
Avenet, Patrick
Oury-Donat, Florence
Perrault, Ghislaine
Griebel, Guy
George, Pascal
Soubrié, Philippe
Scatton, Bernard
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_springer_journals_10_1038_sj_npp_1300772
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_springer_journals_10_1038_sj_npp_1300772
Other Identifiers
ISSN
0893-133X
E-ISSN
1740-634X
DOI
10.1038/sj.npp.1300772
