Bioinstructive implantable scaffolds for rapid in vivo manufacture and release of CAR-T cells
Bioinstructive implantable scaffolds for rapid in vivo manufacture and release of CAR-T cells
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
Despite their clinical success, chimeric antigen receptor (CAR)-T cell therapies for B cell malignancies are limited by lengthy, costly and labor-intensive ex vivo manufacturing procedures that might lead to cell products with heterogeneous composition. Here we describe an implantable Multifunctional Alginate Scaffold for T Cell Engineering and Rel...
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Bioinstructive implantable scaffolds for rapid in vivo manufacture and release of CAR-T cells
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TN_cdi_swepub_primary_oai_DiVA_org_hj_58953
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_hj_58953
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ISSN
1087-0156,1546-1696
E-ISSN
1546-1696
DOI
10.1038/s41587-022-01245-x