Total biosynthesis of the cyclic AMP booster for skolin from Coleus forskohlii
Total biosynthesis of the cyclic AMP booster for skolin from Coleus forskohlii
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English
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Forskolin is a unique structurally complex labdane-type diterpenoid used in the treatment of glaucoma and heart failure based on its activity as a cyclic AMP booster. Commercial production of forskolin relies exclusively on extraction from its only known natural source, the plant Coleus forskohlii, in which forskolin accumulates in the root cork. H...
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Total biosynthesis of the cyclic AMP booster for skolin from Coleus forskohlii
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TN_cdi_swepub_primary_oai_DiVA_org_kth_206294
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_kth_206294
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.23001