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Oral delivery of systemic monoclonal antibodies, peptides and small molecules using gastric auto-inj...

Oral delivery of systemic monoclonal antibodies, peptides and small molecules using gastric auto-inj...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_kth_327853

Oral delivery of systemic monoclonal antibodies, peptides and small molecules using gastric auto-injectors

About this item

Full title

Oral delivery of systemic monoclonal antibodies, peptides and small molecules using gastric auto-injectors

Publisher

New York: Nature Publishing Group US

Journal title

Nature biotechnology, 2022-01, Vol.40 (1), p.103-109

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Oral administration provides a simple and non-invasive approach for drug delivery. However, due to poor absorption and swift enzymatic degradation in the gastrointestinal tract, a wide range of molecules must be parenterally injected to attain required doses and pharmacokinetics. Here we present an orally dosed liquid auto-injector capable of deliv...

Alternative Titles

Full title

Oral delivery of systemic monoclonal antibodies, peptides and small molecules using gastric auto-injectors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_DiVA_org_kth_327853

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_kth_327853

Other Identifiers

ISSN

1087-0156,1546-1696

E-ISSN

1546-1696

DOI

10.1038/s41587-021-01024-0

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